RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
HMGA2
RNA ID
RNA Type
lncrna
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
qRT-PCR; Cell Counting Kit-8 assays;dual-luciferase reporter assay etc.
Target
NA
Pathway
NA
PubMed ID
Title
"LncRNA HCP5 knockdown inhibits high glucose-induced excessive proliferation, fibrosis and inflammation of human glomerular mesangial cells by regulating the miR-93-5p/HMGA2 axis"
Year
2021
Function
"HMGA2 was a target of miR-93-5p, and HMGA2 overexpression abolished the effects of miR-93-5p restoration. HCP5 knockdown inhibited the AKT/mTOR signaling pathway."